When Cells Undermine Their Own Purpose – Part 2
Dear Longevity Insider,
More on cellular senescence...
When a cell enters senescence and it stops producing copies of itself, it excretes hundreds of proteins, which in moderation in healthy tissue, signal the immune system to initiate cellular housekeeping, called autophagy, and start the repair process.
However, when disease and aging cause extensive damage in the tissues, senescent cells build up and stay in a state of suspended animation – not alive, but not quite dead. Some scientists call these twilight cells, and others go for a more Hollywood description of zombie cells because they can negatively affect surrounding cells if not cleared efficiently by the immune system.
Again, from my book, The Longevity Equation, “Unlike other damaged cells, zombie cells don’t self-destruct or clear out of the way to make room for healthy cells. Instead, they stick around and interfere with the body’s natural rebuilding and replenishing mechanisms. . .”
Senescent cells cross the threshold from being protective to deleterious when their accumulation causes them to excrete an overabundance of molecules like pro-inflammatory cytokines, growth factors, and proteases that affect the function of nearby cells and incite local inflammation.
Can we clean up the excess?
While there is no magic bullet and research is still learning how to extend our lifespan and our healthspan, studies on cellular senescence are very promising and it seems as though therapies are on the horizon.
“That getting rid of senescent cells is enough to effectively rejuvenate an animal—that tells you they’re a really important driver of aging,” says Lorna Harries, a molecular geneticist at the University of Exeter in the UK who studies cell senescence.
In the meantime, I have developed a potent blend of phytonutrients that can help stimulate autophagy and dramatically enhance the number of senescent cells that your body can eliminate. It’s the only supplement of its kind that's designed to work on a cellular level to help flush toxic senescent cells out of your body and pave the way for fresh, new, rejuvenating cells to take their place.
It’s called Restori-Cell, and it gives you a way to rewrite the script and change the way you think about aging. It's created to boost mental clarity, promote youthful, all-day energy and support a natural, healthy weight. Restori-Cell meets the highest standards of quality and features five highly specialized nutrients in scientifically supported doses.
Here's the science behind it.
To your longevity,
Anil Bajnath MD
CEO/Founder, Institute for Human Optimization
Chief Medical Officer, Longevity Insider HQ